Synthesis of 5 - Methoxycarbonyl - 1 l - methylfuro ( 2 , 3 - c ) acridan - 6 ( 11 H ) ones

نویسنده

  • P. Shanmugam
چکیده

The plant family Rutaceae is known [1, 2] to be a prolific source of furoquinoline and pyranoquinoline alkaloids. Along with them acridine alka­ loids [3, 4] have also been isolated from several members of the same plant family. Recently furanfused acridine systems such as 1 l-methylfuro(2,3-c)acridan-6(l lH)one (1) have also been reported [5-7] to occur in some rutaceous plants. Typical examples of its naturally occurring derivatives are the alkaloids furofoline-I (2) [6, 7] and furofoline-II (3) [7].

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Synthesis and Crystal Structure Characterization of Zinc (II) Tetronic Acid Complexes

The synthesis and characterization of two new tetronic acid zinc (II) complexes of the empirical formulae [Zn(L-H)(2)(H(2)O)(2)] (1) and [Zn(L-H)(2)(H(2)O)(MeOH)]H(2)O (2) found within the same crystal are reported. The zinc ions bind through alkoxide and carbonyl groups of the ligand 3-methoxycarbonyl-5-phenyl tetronic acid (LH) as indicated by (1)H NMR and X-ray crystallographic studies. Thes...

متن کامل

Trimethoxyphenylverbindungen, XI [1] Inhaltsstoffe von Hagenia abyssinica, 2: Synthese einkerniger Phloracylophenone Trimethoxyphenyl Compounds, XI [1] Constituents of Hagenia abyssinica, 2: Synthesis of Phloracylophenones Containing One Phloroglucinol Unit

Wir hatten aus Flores koso (Hagenia abyssinica) drei einkernige Phloracylophenone, die Kosine K6, K8 und K16, isoliert und — vornehmlich aus ihren Spektren — die Formeln l a , b (K6), 2a, b (K8) und l c (K16) abgeleitet [1]. Wie bereits für K16 [1], wollten wir diese Zuordnung auch für K6 und K8 durch Synthese überprüfen. Zunächst wurde eine in allen Stufen optimierte Synthese von Pseudoaspidin...

متن کامل

Alkinol- und Alkindiol-substituierte Titanocen-Komplexe; Synthese, Reaktionsverhalten und Strukturmerkmale Alkyne-ol and Alkyne-diol Substituted Titanocene Complexes; Synthesis, Reaction Behaviour and Structural Features

The reaction of (//5-C ,H 4SiM e3)2TiC b (1) with H O (C H ^)„C =C R (2a: n = 1, R = H; 2b: n = 1, R = C H 3; 2c: n = 1, R = C H 2O H; 3: n = 2, R = H; 4: n = 4, R = H) affords in toluene at 25 °C in the presence of N E t3 the m onoalkyne-ol substituted titanocenes (/75-C5H 4SiM e3)2T i(C l)[0 (C H ,)„C = C R ] (5a: n = 1. R = H; 5b: n = 1, R = C H 3; 5c: n = 1, R = C H 2O H: 6: n = 2, R = H; 7...

متن کامل

Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs

A series of 3-[2'-(Substitutedbenzylideneamino)phenyl]-2-methyl-6-substituted quinazolin-4-ones (5-10), 3-[2'-(3(″)-chloro-2(″)-oxo-4(″)-substitutedphenylazetidin-1(″)-yl)phenyl]-2-methyl-6-substitutedquinazolin-4-ones (11-16), and 3-[2'-(2(″)-substitutedphenyl-4(″)-oxo-1(″),3(″)-thiazolidin-3(″)-yl)phentl]-2-methyl-6-substitutedquinazolin-4-ones (17-22) have been synthesized in the present stu...

متن کامل

Reactivity of acyclic (pentadienyl)iron(1+) cations: synthetic studies directed toward the frondosins.

A short, 4-step route to the scaffold of frondosin A and B is reported. The [1-methoxycarbonyl-5-(2',5'-dimethoxyphenyl)pentadienyl]Fe(CO)(3)(+) cation was prepared in two steps from (methyl 6-oxo-2,4-hexadienoate)Fe(CO)(3). Reaction of this cation with isopropenyl Grignard or cyclohexenyllithium reagents affords (2-alkenyl-5-aryl-1-methoxycarbonyl-3-pentene-1,5-diyl)Fe(CO)(3) along with other ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013